2,6-Diisopropylphenyl isocyanate → HCID 25190996, compound

HRID 2061650Notes

Reaction equation

HRID 2061650 reaction equation
[CH2:1]([S:8][C:9]1([CH2:15][NH2:16])[CH2:14][CH2:13][CH2:12][CH2:11][CH2:10]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH:17]([C:20]1[CH:25]=[CH:24][CH:23]=[C:22]([CH:26]([CH3:28])[CH3:27])[C:21]=1[N:29]=[C:30]=[O:31])([CH3:19])[CH3:18]>>[CH2:1]([S:8][C:9]1([CH2:15][NH:16][C:30]([NH:29][C:21]2[C:20]([CH:17]([CH3:18])[CH3:19])=[CH:25][CH:24]=[CH:23][C:22]=2[CH:26]([CH3:28])[CH3:27])=[O:31])[CH2:14][CH2:13][CH2:12][CH2:11][CH2:10]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 922592,6-Diisopropylphenyl isocyanateHCID 14613838HCID 14613838, compound

Product 1

HCID 25190996HCID 25190996, compoundYield 45.1%

Procedure

Similarly to Example 1(c), by reaction of 120 mg (0.51 mmol) of C-(1-benzylsulfanyl-cyclohexyl)-methylamine with 125 μl (0.61 mmol) of 2,6-diisopropylphenylisocyanate. 101 mg of 1-(1-benzylsulfanyl-cyclohexylmethyl)-3-(2,6-diisopropyl-phenyl)-urea is obtained in the form of a white solid. (m.p.=156° C., Yields 45%).

Sources & evidence

ORD record
ord-c39654003d2f44a49ac0a89148152f47
Source dataset
uspto-grants-2012_10
Patent number
US08283378B2

Reaction notes

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