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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2061692Generated: November 1, 2026

(R)-1-Benzyl-5-carboxy-2-pyrrolidinone → Ethyl 3-((R)-1-benzyl-5-oxopyrrolidine-2-carboxamido)-2-hydroxy-4-phenylbutanoate

https://huagongshe.com/reaction/2061692

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(R)-1-Benzyl-5-carboxy-2-pyrrolidinoneHCID 23390401—
ReactantHCID 86644788HCID 86644788—
ProductEthyl 3-((R)-1-benzyl-5-oxopyrrolidine-2-carboxamido)-2-hydroxy-4-phenylbutanoateHCID 66644659—

Reaction Steps

The reaction was carried out in analogy to reaction step 20.1 of Example 20 by reacting (R)-1-benzyl-5-oxopyrrolidine-2-carboxylic acid and 4-ethoxy-3-hydroxy-4-oxo-1-phenylbutan-2-aminium chloride. ESI-MS [M+H]+=425.2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08283363B2
Source datasetuspto-grants-2012_10
ORD IDord-13d0d7759890421fb504d1b5aa75b186
Source noteuspto-grants-2012_10