HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydroxylamine, O-(1-methylethyl)- → (2R)-1-benzyl-N-(3-hydroxy-4-(isopropoxyamino)-4-oxo-1-phenylbutan-2-yl)-5-oxopyrrolidine-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydroxylamine, O-(1-methylethyl)- | HCID 2768923 | — |
| Reactant | 3-((R)-1-Benzyl-5-oxopyrrolidine-2-carboxamido)-2-hydroxy-4-phenylbutanoic Acid | HCID 66644572 | — |
| Product | (2R)-1-benzyl-N-(3-hydroxy-4-(isopropoxyamino)-4-oxo-1-phenylbutan-2-yl)-5-oxopyrrolidine-2-carboxamide | HCID 86652463 | — |
Reaction Steps
The reaction can be carried out in analogy to reaction step 20.3 by reacting 3-((R)-1-benzyl-5-oxopyrrolidine-2-carboxamido)-2-hydroxy-4-phenylbutanoic acid with O-isopropylhydroxylamine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08283363B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-832c91031bc440e2b4fb49c99fa45634 |
| Source note | uspto-grants-2012_10 |