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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2061724Generated: October 25, 2026

1-(Pyrazin-2-yl)ethanamine → 5-(Ethyl-isobutyryl-amino)-4'-methyl-biphenyl-3-carboxylic acid (1-pyrazin-2-yl-ethyl)-amide

https://huagongshe.com/reaction/2061724

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(Pyrazin-2-yl)ethanamineHCID 18519006—
Reactant5-(Ethyl-isobutyryl-amino)-4'-methyl-biphenyl-3-carboxylic acidHCID 59627533—
Product5-(Ethyl-isobutyryl-amino)-4'-methyl-biphenyl-3-carboxylic acid (1-pyrazin-2-yl-ethyl)-amideHCID 49848201—

Reaction Steps

5-(Ethyl-isobutyryl-amino)-4′-methyl-biphenyl-3-carboxylic acid was reacted with 1-pyrazin-2-yl-ethylamine following the procedure of step 5 of Example 1 to give 5-(ethyl-isobutyryl-amino)-4′-methyl-biphenyl-3-carboxylic acid (1-pyrazin-2-yl-ethyl)-amide, MS (M+H)=431.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08283383B2
Source datasetuspto-grants-2012_10
ORD IDord-fa3af0ce16874332adc10157f855f649
Source noteuspto-grants-2012_10