HCID 11589278, compound → HCID 11582251, compound

HRID 2062073Notes

Reaction equation

HRID 2062073 reaction equation
COC1N=CC(COC2C3C(=CC=CC=3)C=CC=2C(NC(C)(C)C(O)=O)=O)=CC=1.C[O:31][C:32](=[O:60])[C:33]([NH:37][C:38]([C:40]1[CH:49]=[CH:48][C:47]2[C:42](=[CH:43][CH:44]=[CH:45][CH:46]=2)[C:41]=1[O:50][CH2:51][C:52]1[CH:53]=[N:54][C:55]([O:58][CH3:59])=[CH:56][CH:57]=1)=[O:39])([CH3:36])[CH2:34][CH3:35]>>[CH3:59][O:58][C:55]1[N:54]=[CH:53][C:52]([CH2:51][O:50][C:41]2[C:42]3[C:47](=[CH:46][CH:45]=[CH:44][CH:43]=3)[CH:48]=[CH:49][C:40]=2[C:38]([NH:37][C:33]([CH3:36])([CH2:34][CH3:35])[C:32]([OH:60])=[O:31])=[O:39])=[CH:57][CH:56]=1

Participants

3

Reactant 2

HCID 11589278HCID 11589278, compoundHCID 66701243HCID 66701243, compound

Product 1

HCID 11582251HCID 11582251, compound

Procedure

2-{[1-(6-Methoxy-pyridin-3-ylmethoxy)-naphthalene-2-carbonyl]-amino}-2-methyl-butyric acid was prepared in similar manner as 2-{[1-(6-methoxy-pyridin-3-ylmethoxy)-naphthalene-2-carbonyl]-amino}-2-methyl-propionic acid (example 152) via 2-{[1-(6-Methoxy-pyridin-3-ylmethoxy)-naphthalene-2-carbonyl]-amino}-2-methyl-butyric acid methyl ester (C24H26N2O5 (422.49), LCMS (ESI): 423.15 (MH+)).

Sources & evidence

ORD record
ord-c041411ec7cb4f7aa480d99fbe10e9ee
Source dataset
uspto-grants-2012_10
Patent number
US08283479B2

Reaction notes

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