HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Naphthalenecarboxylic acid, 1-hydroxy-, methyl ester → HCID 66701115, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Naphthalenecarboxylic acid, 1-hydroxy-, methyl ester | HCID 70358 | — |
| Reactant | 5-(Chloromethyl)-2-(trifluoromethyl)pyridine | HCID 2773810 | — |
| Reactant | HCID 66701337 | HCID 66701337 | — |
| Product | HCID 66701115 | HCID 66701115 | — |
Reaction Steps
In analogy to steps a) and b) of example 3 starting from 1-hydroxy-naphthalene-2-carboxylic acid methyl ester using 5-chloromethyl-2-trifluoromethyl-pyridine and and performing the amidation reaction using 2-amino-2-methyl-propionitrile 1-(6-trifluoromethyl-pyridin-3-ylmethoxy)-naphthalene-2-carboxylic acid (cyano-dimethyl-methyl)-amide was obtained as a brown oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08283479B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-d8e05ef5157b4eb891b2e6bdd3bcbeab |
| Source note | uspto-grants-2012_10 |