Acetic Acid → Ethyl 4-(2-fluoro-4-iodoanilino)-6-oxo-1,6-dihydro-3-pyridinecarboxylate

HRID 206218Notes

Reaction equation

HRID 206218 reaction equation
[CH3:23][C:24](=[O:25])[OH:26].[Cl:1][c:2]1[n:3][cH:4][c:5]([C:6](=[O:7])[O:8][CH2:9][CH3:10])[c:11]([NH:13][c:14]2[c:15]([F:21])[cH:16][c:17]([I:20])[cH:18][cH:19]2)[cH:12]1.[OH2:22]>>[c:2]1(=[O:22])[nH:3][cH:4][c:5]([C:6](=[O:7])[O:8][CH2:9][CH3:10])[c:11]([NH:13][c:14]2[c:15]([F:21])[cH:16][c:17]([I:20])[cH:18][cH:19]2)[cH:12]1

Participants

4

Reactant 3

HCID 176Acetic AcidHCID 962WaterHCID 23631002Ethyl 6-chloro-4-(2-fluoro-4-iodoanilino)nicotinate

Product 1

HCID 23630800Ethyl 4-(2-fluoro-4-iodoanilino)-6-oxo-1,6-dihydro-3-pyridinecarboxylate

Sources & evidence

ORD record
ord-f83bf6dadf3d447ca3f69b9ef0bba74f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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