2-Chloro-4-trifluoromethyl-5-thiazolecarbonyl chloride → Methyl 5-{[2-Chloro-4-(trifluoromethyl)-5-thiazolyl]carbonylamino}-2-(difluoromethyl)-4-(2-methylpropyl)-6-(trifluoromethyl)-3-pyridinecarboxylate
Reaction equation
[Cl:23][c:24]1[s:25][c:26]([C:33](=[O:34])[Cl:35])[c:27]([C:29]([F:30])([F:31])[F:32])[n:28]1.[NH2:1][c:2]1[c:3]([CH2:19][CH:20]([CH3:21])[CH3:22])[c:4]([C:15](=[O:16])[O:17][CH3:18])[c:5]([CH:12]([F:13])[F:14])[n:6][c:7]1[C:8]([F:9])([F:10])[F:11]>>[NH:1]([c:2]1[c:3]([CH2:19][CH:20]([CH3:21])[CH3:22])[c:4]([C:15](=[O:16])[O:17][CH3:18])[c:5]([CH:12]([F:13])[F:14])[n:6][c:7]1[C:8]([F:9])([F:10])[F:11])[C:33]([c:26]1[s:25][c:24]([Cl:23])[n:28][c:27]1[C:29]([F:30])([F:31])[F:32])=[O:34]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-0e04135701734bdb829aede8aaab79ce
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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