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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 206254Generated: October 26, 2026

Tetrahydrofuran → Tert-butyl 4-[(2,5-difluorophenyl)(hydroxy)methyl]piperidine-1-carboxylate

https://huagongshe.com/reaction/206254

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
Reactant2-Bromo-1,4-difluorobenzeneHCID 67862—
Reactanttert-Butyl 4-formylpiperidine-1-carboxylateHCID 1514430—
ReactantButyllithiumHCID 178418339—
ProductTert-butyl 4-[(2,5-difluorophenyl)(hydroxy)methyl]piperidine-1-carboxylateHCID 69344572—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-e1e453b37c774150827cc6e2bd440ec0
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)