Ammonia → HCID 135585887, compound

HRID 2063165Notes

Reaction equation

HRID 2063165 reaction equation
[O:1]=[C:2]1[C:7]([C:8]([O:10]CC)=O)=[N:6][N:5]=[CH:4][NH:3]1.[NH3:13]>C(O)C>[O:1]=[C:2]1[C:7]([C:8]([NH2:13])=[O:10])=[N:6][N:5]=[CH:4][NH:3]1

Participants

4

Reactant 2

HCID 222Ammonia2×HCID 135585888HCID 135585888, compound

Product 1

HCID 135585887HCID 135585887, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

In 5 mL of ethanol is dissolved 0.06 g of ethyl 5-oxo-4,5-dihydro-1,2,4-triazine-6-carboxylate. At 10° C., the solution is saturated with ammonia by introducing gaseous ammonia thereinto for 20 minutes. The solution is allowed to stand at ambient temperature for 15 hours, and the resulting crystals are collected by filtration. The crystals thus obtained are washed successively with two 2 mL portions of ethanol and then two 1 mL portion of methanol to obtain 0.03 g of 5-oxo-4,5-dihydro-1,2,4-triazine-6-carboxamide.

Workup

  1. customAt 10° C.
  2. waitto stand at ambient temperature for 15 hours
  3. filtrationthe resulting crystals are collected by filtration
  4. customThe crystals thus obtained
  5. washare washed successively with two 2 mL portions of ethanol

Sources & evidence

ORD record
ord-2f9607f6c8e4439ca9c276b3e38a2df1
Source dataset
uspto-grants-2012_10
Patent number
USRE043748E1

Reaction notes

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