HuagongsheHuagongshe Chemistry Print Report · For research reference only
ethyl 5-fluoro-1H-indole-2-carboxylate → ethyl 5-fluoro-1-[2-[(5-methylpyridin-2-yl)oxy]-ethyl]-1H-indole-2-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | ethyl 5-fluoro-1H-indole-2-carboxylate | HCID 2727899 | — |
| Reactant | 2-[(5-Methylpyridin-2-yl)oxy]ethanol | HCID 20795169 | — |
| Product | ethyl 5-fluoro-1-[2-[(5-methylpyridin-2-yl)oxy]-ethyl]-1H-indole-2-carboxylate | HCID 66811445 | — |
Reaction Steps
The ethyl 5-fluoro-1-[2-[(5-methylpyridin-2-yl)oxy]-ethyl]-1H-indole-2-carboxylate intermediate is prepared in a manner similar to the method described in Example 18.1, from ethyl 5-fluoro-1H-indole-2-carboxylate and 2-(5-methylpyridin-2-yloxy)ethanol prepared in the preceding step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08288376B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-5e9187a751514a87ba6de4223fccfdd5 |
| Source note | uspto-grants-2012_10 |