HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(p-acetylphenyl)acetamide → N-(4-{1-[(2-Methyl-6-phenyl-pyrimidin-4-yl)-hydrazono]-ethyl}-phenyl)-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(p-acetylphenyl)acetamide | HCID 75937 | — |
| Reactant | 4-Hydrazino-2-methyl-6-phenylpyrimidine trihydrochloride | HCID 60209694 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | N-(4-{1-[(2-Methyl-6-phenyl-pyrimidin-4-yl)-hydrazono]-ethyl}-phenyl)-acetamide | HCID 73320071 | — |
Reaction Steps
The title compound was prepared from 4-hydrazino-2-methyl-6-phenylpyrimidine trihydrochloride (300 mg, 0.97 mmol) and N-(4-acetyl-phenyl)acetamide (515 mg, 2.91 mmol) in ethanol (10.0 mL) by a procedure similar to example 1, step 4 yielding 43 mg (12%) of a brown solid. HPLC Purity: 95%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08288398B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-a1394acfc6204d2fabe3f8db814c4335 |
| Source note | uspto-grants-2012_10 |