1,5-dimethyl-1H-pyrazol-3-amine → HCID 59324074, compound

HRID 2063627Notes

Reaction equation

HRID 2063627 reaction equation
Br[C:2]1[CH:3]=[CH:4][C:5]([N:10]2[CH:14]=[C:13]([CH3:15])[N:12]=[CH:11]2)=[C:6]([CH:9]=1)[C:7]#[N:8].[CH3:16][N:17]1[C:21]([CH3:22])=[CH:20][C:19]([NH2:23])=[N:18]1>>[CH3:16][N:17]1[C:21]([CH3:22])=[CH:20][C:19]([NH:23][C:2]2[CH:3]=[CH:4][C:5]([N:10]3[CH:14]=[C:13]([CH3:15])[N:12]=[CH:11]3)=[C:6]([CH:9]=2)[C:7]#[N:8])=[N:18]1

Participants

3

Reactant 2

HCID 70177471,5-dimethyl-1H-pyrazol-3-amineHCID 669615175-bromo-2-(4-methyl-1H-imidazol-1-yl)benzonitrile

Product 1

HCID 59324074HCID 59324074, compound

Procedure

Prepared in analogy to example 1b) starting with 5-bromo-2-(4-methyl-imidazol-1-yl)-benzonitrile and 1,5-dimethyl-1H-pyrazol-3-ylamine. The title compound was obtained as a yellowish solid (Yield=36%). MS ISP (m/e): 293.2 (100) [(M+H)+].

Workup

  1. customPrepared in analogy to example 1b)

Sources & evidence

ORD record
ord-7f749d8c901a49dd870fd208aac718c0
Source dataset
uspto-grants-2012_10
Patent number
US08288403B2

Reaction notes

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