HCID 60911320, compound → HCID 59324072, compound

HRID 2063632Notes

Reaction equation

HRID 2063632 reaction equation
Br[C:2]1[CH:3]=[CH:4][C:5]([N:10]2[CH:14]=[C:13]([CH3:15])[N:12]=[CH:11]2)=[C:6]([CH:9]=1)[C:7]#[N:8].[CH:16]1([CH2:19][N:20]2[CH:24]=[N:23][C:22]([NH2:25])=[N:21]2)[CH2:18][CH2:17]1>>[CH:16]1([CH2:19][N:20]2[CH:24]=[N:23][C:22]([NH:25][C:2]3[CH:3]=[CH:4][C:5]([N:10]4[CH:14]=[C:13]([CH3:15])[N:12]=[CH:11]4)=[C:6]([CH:9]=3)[C:7]#[N:8])=[N:21]2)[CH2:18][CH2:17]1

Participants

3

Reactant 2

HCID 60911320HCID 60911320, compoundHCID 669615175-bromo-2-(4-methyl-1H-imidazol-1-yl)benzonitrile

Product 1

HCID 59324072HCID 59324072, compound

Procedure

Prepared in analogy to example 1b) starting with 5-bromo-2-(4-methyl-imidazol-1-yl)-benzonitrile and 1-cyclopropylmethyl-1H-[1,2,4]triazol-3-ylamine. The title compound was obtained as a yellowish foam (Yield=45%). MS ISP (m/e): 320.1 (100) [(M+H)+].

Workup

  1. customPrepared in analogy to example 1b)

Sources & evidence

ORD record
ord-792ba142ac0a4ac88c6461738885b47a
Source dataset
uspto-grants-2012_10
Patent number
US08288403B2

Reaction notes

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