4-Methyloxybenzyl chloride → 1-((4-methoxyphenyl)methyl)-1H-1,2,4-triazol-3-amine

HRID 2063636Notes

Reaction equation

HRID 2063636 reaction equation
[NH2:1][C:2]1[N:6]=[CH:5][NH:4][N:3]=1.[CH3:7][O:8][C:9]1[CH:16]=[CH:15][C:12]([CH2:13]Cl)=[CH:11][CH:10]=1>>[CH3:7][O:8][C:9]1[CH:16]=[CH:15][C:12]([CH2:13][N:4]2[CH:5]=[N:6][C:2]([NH2:1])=[N:3]2)=[CH:11][CH:10]=1

Participants

3

Reactant 2

HCID 699934-Methyloxybenzyl chlorideHCID 178418311HCID 178418311, compound

Product 1

HCID 609114561-((4-methoxyphenyl)methyl)-1H-1,2,4-triazol-3-amine

Procedure

Prepared in analogy to example 3a) starting with 3-amino-1,2,4-triazole and 4-methoxy benzyl chloride. The title compound was obtained as a colorless solid, MS ISP (m/e): 205.2 (100) [(M+H)+].

Workup

  1. customPrepared in analogy to example 3a)

Sources & evidence

ORD record
ord-b3c3b92edca2434e99bbed3feef6c6f0
Source dataset
uspto-grants-2012_10
Patent number
US08288403B2

Reaction notes

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