2-Chlorobenzyl chloride → 1-[(2-Chlorophenyl)methyl]-1H-1,2,4-triazol-3-amine

HRID 2063638Notes

Reaction equation

HRID 2063638 reaction equation
[NH2:1][C:2]1[N:6]=[CH:5][NH:4][N:3]=1.[Cl:7][C:8]1[CH:15]=[CH:14][CH:13]=[CH:12][C:9]=1[CH2:10]Cl>>[Cl:7][C:8]1[CH:15]=[CH:14][CH:13]=[CH:12][C:9]=1[CH2:10][N:4]1[CH:5]=[N:6][C:2]([NH2:1])=[N:3]1

Participants

3

Reactant 2

HCID 119062-Chlorobenzyl chlorideHCID 178418311HCID 178418311, compound

Product 1

HCID 70193311-[(2-Chlorophenyl)methyl]-1H-1,2,4-triazol-3-amine

Procedure

Prepared in analogy to example 3a) starting with 3-amino-1,2,4-triazole and 2-chloro benzyl chloride. The title compound was obtained as a colorless oil (Yield=11%). MS ISP (m/e): 209.0 & 211.0 (100 & 44) [(M+H)+].

Workup

  1. customPrepared in analogy to example 3a)

Sources & evidence

ORD record
ord-0dd0cb40af6749f19f2b24d99675d999
Source dataset
uspto-grants-2012_10
Patent number
US08288403B2

Reaction notes

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