HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aniline → 1-phenyl-1H-1,2,4-triazol-3-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aniline | HCID 6115 | — |
| Reactant | 5-Phenyl-1,2,4-oxadiazol-3-amine | HCID 2305446 | — |
| Product | 1-phenyl-1H-1,2,4-triazol-3-amine | HCID 21821744 | 87% |
Reaction Steps
This compound was prepared from 5-phenyl-[1,2,4]oxadiazol-3-ylamine (Journal of Organic Chemistry 28, 1812 (1963) and aniline, via the rearrangement described by Ruccia et al., Journal of Heterocyclic Chemistry 8, 137 (1971). The title compound was isolated as a slightly brownish solid in a yield of 87%. MS ISP (m/e): 161.2 (100) [(M+H)+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08288403B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-b489db41bb9b418ba091df64ab8fc0b1 |
| Source note | uspto-grants-2012_10 |