1-[(2,4-Dichlorophenyl)methyl]-1H-1,2,4-triazol-3-amine → HCID 46216253, compound

HRID 2063663Notes

Reaction equation

HRID 2063663 reaction equation
Br[C:2]1[CH:3]=[CH:4][C:5]([N:10]2[CH:14]=[C:13]([CH3:15])[N:12]=[CH:11]2)=[C:6]([CH:9]=1)[C:7]#[N:8].[Cl:16][C:17]1[CH:29]=[C:28]([Cl:30])[CH:27]=[CH:26][C:18]=1[CH2:19][N:20]1[CH:24]=[N:23][C:22]([NH2:25])=[N:21]1>>[Cl:16][C:17]1[CH:29]=[C:28]([Cl:30])[CH:27]=[CH:26][C:18]=1[CH2:19][N:20]1[CH:24]=[N:23][C:22]([NH:25][C:2]2[CH:3]=[CH:4][C:5]([N:10]3[CH:14]=[C:13]([CH3:15])[N:12]=[CH:11]3)=[C:6]([CH:9]=2)[C:7]#[N:8])=[N:21]1

Participants

3

Reactant 2

HCID 70193351-[(2,4-Dichlorophenyl)methyl]-1H-1,2,4-triazol-3-amineHCID 669615175-bromo-2-(4-methyl-1H-imidazol-1-yl)benzonitrile

Product 1

HCID 46216253HCID 46216253, compound

Procedure

Prepared in analogy to example 1b) starting with 5-bromo-2-(4-methyl-imidazol-1-yl)-benzonitrile and 1-(2,4-dichloro-benzyl)-1H-[1,2,4]triazol-3-ylamine (ART-CHEM). The title compound was obtained as a colorless solid (Yield=67%). MS ISP (m/e): 424.1 (100) & 426.0 (81) [(M+H)+].

Workup

  1. customPrepared in analogy to example 1b)

Sources & evidence

ORD record
ord-b3f5ee6b50c94159ab58b819aa4774c7
Source dataset
uspto-grants-2012_10
Patent number
US08288403B2

Reaction notes

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