HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4,5-Trifluorobenzyl bromide → 1-(3,4,5-Trifluoro-benzyl)-1H-pyrazol-3-ylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4,5-Trifluorobenzyl bromide | HCID 2777062 | — |
| Reactant | HCID 178418806 | HCID 178418806 | — |
| Product | 1-(3,4,5-Trifluoro-benzyl)-1H-pyrazol-3-ylamine | HCID 67342971 | — |
Reaction Steps
Prepared in analogy to example 10a) starting with 3-amino-1H-pyrazole and 3,4,5-trifluorobenzyl bromide. The title compound was obtained as a brown oil (Yield=31%). MS ISP (m/e): 228.2 (100) [(M+H)+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08288403B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-799a6bb72578439faaa878594084376d |
| Source note | uspto-grants-2012_10 |