4-Chlorobenzohydrazide → HCID 59324063, compound

Participants

Reaction Steps

A solution of mercury-(II)-oxide (97 mg, 0.45 mmol) in 5 ml of methanol was treated with 1,3-bis-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-thiourea (200 mg, 0.45 mmol) and 4-chloro-benzhydrazide (76 mg, 0.45 mmol). The resulting mixture was refluxed for 3 hours, concentrated and triturated with ethyl acetate. Filtering of the suspension and chromatography on silica gel using ethyl acetate as eluent gave the title compound as a brownish solid (14 mg, 8%).

Provenance & Evidence