2-Chloroaniline → 1-(2-Chloro-phenyl)-1H-[1,2,4]triazol-3-ylamine

HRID 2063678Notes

Reaction equation

HRID 2063678 reaction equation
C1([C:7]2O[N:10]=[C:9]([NH2:12])[N:8]=2)C=CC=CC=1.[Cl:13][C:14]1[CH:20]=[CH:19][CH:18]=[CH:17][C:15]=1[NH2:16]>>[Cl:13][C:14]1[CH:20]=[CH:19][CH:18]=[CH:17][C:15]=1[N:16]1[CH:7]=[N:8][C:9]([NH2:12])=[N:10]1

Participants

3

Reactant 2

HCID 72402-ChloroanilineHCID 23054465-Phenyl-1,2,4-oxadiazol-3-amine

Product 1

HCID 673780411-(2-Chloro-phenyl)-1H-[1,2,4]triazol-3-ylamine

Procedure

Prepared in analogy to example 18a), starting with 5-phenyl-[1,2,4]oxadiazol-3-ylamine and 2-chloroaniline. The title compound was obtained as brownish solid (Yield=61%). MS ISP (m/e): 195.1 (100) [(M+H)+].

Workup

  1. customPrepared in analogy to example 18a),

Sources & evidence

ORD record
ord-4c4bd9bacf7e40ac931021a4337af35a
Source dataset
uspto-grants-2012_10
Patent number
US08288403B2

Reaction notes

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