HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-bromo-2-(4-methyl-1H-imidazol-1-yl)benzonitrile → 5-[1-(2-Chloro-phenyl)-1H-[1,2,4]triazol-3-ylamino]-2-(4-methyl-imidazol-1-yl)-benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-bromo-2-(4-methyl-1H-imidazol-1-yl)benzonitrile | HCID 66961517 | — |
| Reactant | 1-(2-Chloro-phenyl)-1H-[1,2,4]triazol-3-ylamine | HCID 67378041 | — |
| Product | 5-[1-(2-Chloro-phenyl)-1H-[1,2,4]triazol-3-ylamino]-2-(4-methyl-imidazol-1-yl)-benzonitrile | HCID 46214244 | — |
Reaction Steps
Prepared in analogy to example 1b) starting with 5-bromo-2-(4-methyl-imidazol-1-yl)-benzonitrile and 1-(2-chloro-phenyl)-1H-[1,2,4]triazol-3-ylamine. The title compound was obtained as a colorless solid (Yield=27%). MS ISP (m/e): 374.3 (100) [(M+H)+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08288403B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-07ca5daaaa8b41a7adeccb57c7a72719 |
| Source note | uspto-grants-2012_10 |