4-Fluorobenzyl bromide → HCID 1508927, compound

HRID 2063696Notes

Reaction equation

HRID 2063696 reaction equation
[CH3:1][C:2]1[NH:6][N:5]=[C:4]([NH2:7])[CH:3]=1.[F:8][C:9]1[CH:16]=[CH:15][C:12]([CH2:13]Br)=[CH:11][CH:10]=1>>[F:8][C:9]1[CH:16]=[CH:15][C:12]([CH2:13][N:6]2[C:2]([CH3:1])=[CH:3][C:4]([NH2:7])=[N:5]2)=[CH:11][CH:10]=1

Participants

3

Reactant 2

HCID 680214-Fluorobenzyl bromideHCID 931461H-Pyrazol-3-amine, 5-methyl-

Product 1

HCID 1508927HCID 1508927, compound

Procedure

Prepared in analogy to example 10a) starting with 5-methyl-1H-pyrazol-3-ylamine and 4-fluorobenzyl bromide. The title compound was obtained as a white solid (Yield=14%). MS ISP (m/e): 206.1 (100) [(M+H)+].

Workup

  1. customPrepared in analogy to example 10a)

Sources & evidence

ORD record
ord-5eac65c1ab984a40aa493973b9572fc0
Source dataset
uspto-grants-2012_10
Patent number
US08288403B2

Reaction notes

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