HCID 1508927, compound → HCID 46216602, compound

HRID 2063697Notes

Reaction equation

HRID 2063697 reaction equation
Br[C:2]1[CH:7]=[CH:6][C:5]([N:8]2[CH:12]=[C:11]([CH3:13])[N:10]=[CH:9]2)=[C:4]([O:14][CH3:15])[CH:3]=1.[F:16][C:17]1[CH:30]=[CH:29][C:20]([CH2:21][N:22]2[C:26]([CH3:27])=[CH:25][C:24]([NH2:28])=[N:23]2)=[CH:19][CH:18]=1>>[F:16][C:17]1[CH:30]=[CH:29][C:20]([CH2:21][N:22]2[C:26]([CH3:27])=[CH:25][C:24]([NH:28][C:2]3[CH:7]=[CH:6][C:5]([N:8]4[CH:12]=[C:11]([CH3:13])[N:10]=[CH:9]4)=[C:4]([O:14][CH3:15])[CH:3]=3)=[N:23]2)=[CH:19][CH:18]=1

Participants

3

Reactant 2

HCID 1508927HCID 1508927, compoundHCID 534156611-(4-bromo-2-methoxyphenyl)-4-methyl-1H-imidazole

Product 1

HCID 46216602HCID 46216602, compound

Procedure

Prepared in analogy to example 43 starting with 1-(4-bromo-2-methoxy-phenyl)-4-methyl-1H-imidazole and 1-(4-fluoro-benzyl)-5-methyl-1H-pyrazol-3-ylamine. The title compound was obtained as a light yellow oil (Yield=41%). MS ISP (m/e): 392.2 (100) [(M+H)+].

Sources & evidence

ORD record
ord-265d01d58a9740e89f01e4fd9504534c
Source dataset
uspto-grants-2012_10
Patent number
US08288403B2

Reaction notes

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