1-(4-bromo-2-methoxyphenyl)-4-methyl-1H-imidazole → HCID 46214071, compound

HRID 2063705Notes

Reaction equation

HRID 2063705 reaction equation
Br[C:2]1[CH:7]=[CH:6][C:5]([N:8]2[CH:12]=[C:11]([CH3:13])[N:10]=[CH:9]2)=[C:4]([O:14][CH3:15])[CH:3]=1.[C:16]1([CH:22]([N:24]2[CH:28]=[N:27][C:26]([NH2:29])=[N:25]2)[CH3:23])[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[CH3:15][O:14][C:4]1[CH:3]=[C:2]([NH:29][C:26]2[N:27]=[CH:28][N:24]([CH:22]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)[CH3:23])[N:25]=2)[CH:7]=[CH:6][C:5]=1[N:8]1[CH:12]=[C:11]([CH3:13])[N:10]=[CH:9]1

Participants

3

Reactant 2

HCID 534156611-(4-bromo-2-methoxyphenyl)-4-methyl-1H-imidazoleHCID 64120767HCID 64120767, compound

Product 1

HCID 46214071HCID 46214071, compound

Procedure

Prepared in analogy to example 43 starting with 1-(4-bromo-2-methoxy-phenyl)-4-methyl-1H-imidazole and 1-(1-phenyl-ethyl)-1H-[1,2,4]triazol-3-ylamine. The title compound was obtained as a white solid (Yield=66%). MS ISP (m/e): 375.3 (100) [(M+H)+].

Sources & evidence

ORD record
ord-dc85525068ee4162b72bcd61f3ba3126
Source dataset
uspto-grants-2012_10
Patent number
US08288403B2

Reaction notes

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