HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butoxy bis(dimethylamino)methane → 5-Dimethylaminomethylene-6,7-dihydro-5H-benzo[1,2,5]oxadiazol-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butoxy bis(dimethylamino)methane | HCID 79885 | — |
| Reactant | 6,7-Dihydro-2,1,3-benzoxadiazol-4(5H)-one | HCID 543052 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 5-Dimethylaminomethylene-6,7-dihydro-5H-benzo[1,2,5]oxadiazol-4-one | HCID 67405521 | 57.1% |
Reaction Steps
A THF solution of 4,5,6,7-tetrahydro-2,1,3-benzoxadiazole-4-one 1 g (0.00725 mol) and Bredereck's reagent 1.89 g (0.0109 mol) was stirred at room temperature for 2 days. The crystalline precipitate was filtered, washed with THF and dried, 0.8 g desired product was obtained, the yield is 57%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08288400B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-9fe147e6593a4ec79e4b2002676dcadf |
| Source note | uspto-grants-2012_10 |