HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-1-methoxy-2-methylbenzene → HCID 59485111, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-1-methoxy-2-methylbenzene | HCID 608315 | — |
| Reactant | HCID 66759462 | HCID 66759462 | — |
| Product | HCID 59485111 | HCID 59485111 | 41% |
Reaction Steps
By using 1-(7-methoxy-2,4,6-trimethyl-2,3-dihydro-1-benzofuran-5-yl)piperazine (552 mg, 2.0 mmol) synthesized in Reference example 88 and 4-bromo-1-methoxy-2-methylbenzene (804 mg, 4.0 mmol), the reaction was carried out in the same manner as Example 23 to synthesize the title compound 323 mg (yield 41%). Melting point was 94 to 96° C. (ethanol-water).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08288390B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-711680bd46b04a8bb7ced0df70f3bc94 |
| Source note | uspto-grants-2012_10 |