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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2063917Generated: November 2, 2026

1-(4-Fluorophenyl)piperazine → HCID 59485113, compound

https://huagongshe.com/reaction/2063917

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-Fluorophenyl)piperazineHCID 75260—
ReactantHCID 66759547HCID 66759547—
ProductHCID 59485113HCID 59485113154.8%

Reaction Steps

By using 5-bromo-2,2,7-trimethyl-6-(4-methylphenyl)-2,3-dihydro-1-benzofuran (150 mg, 1.49 mmol) synthesized in Reference Example 157 and 1-(4-fluorophenyl)piperazine (82.0 mg, 0.450 mmol), the reaction was carried out in the same manner as Example 129 to obtain 300 mg of the title compound as a colorless solid (yield 15%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08288390B2
Source datasetuspto-grants-2012_10
ORD IDord-92faddd8804f42a2847d24046ea4150d
Source noteuspto-grants-2012_10