HCID 57423903, compound → HCID 57423904, compound

Participants

Reaction Steps

A suspension of D1 (14.0 g, 45 mmol) and 5% Pd/C (3.0 g) in methanol (500 mL) in an autoclave (1000 mL) was put under an atmosphere of hydrogen (˜20 atm). The mixture was stirred at room temperature for 3 hours and then filtered through a pad of celite. The filtrate was concentrated under reduced pressure to give the title compound (12.7 g, 100% yield) as a black solid that was used without further purification. (Rf: 0.3 (ethyl acetate/hexane 7:8))

Provenance & Evidence