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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 206429Generated: October 30, 2026

Acetonitrile → 6-fluoro-3-oxo-2-(4-trifluoromethoxy-benzyl)-2,3-dihydro-1H-isoindole-4-carbonitrile

https://huagongshe.com/reaction/206429

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetonitrileHCID 6342—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
Reactant5-Fluoro-7-iodo-2-(4-trifluoromethoxy-benzyl)-2,3-dihydro-isoindol-1-oneHCID 57949615—
ReactantHCID 178420554HCID 178420554—
ReactantHCID 178511850HCID 178511850—
Product6-fluoro-3-oxo-2-(4-trifluoromethoxy-benzyl)-2,3-dihydro-1H-isoindole-4-carbonitrileHCID 57949476—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-366d607767cb44d581da135db011fa00
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)