2,3-Dihydro-1-benzofuran-4-carboxylic acid → HCID 66844868, compound

HRID 2064486Notes

Reaction equation

HRID 2064486 reaction equation
[O:1]1[C:5]2=[CH:6][CH:7]=[CH:8][C:9]([C:10]([OH:12])=O)=[C:4]2[CH2:3][CH2:2]1.[C:13]([O:17][C:18]([N:20]1[C@H:27]([CH2:28][NH2:29])[CH2:26][C@H:25]2[C@@H:21]1[CH2:22][CH2:23][CH2:24]2)=[O:19])([CH3:16])([CH3:15])[CH3:14]>>[C:13]([O:17][C:18]([N:20]1[C@H:27]([CH2:28][NH:29][C:10]([C:9]2[CH:8]=[CH:7][CH:6]=[C:5]3[O:1][CH2:2][CH2:3][C:4]=23)=[O:12])[CH2:26][C@H:25]2[C@@H:21]1[CH2:22][CH2:23][CH2:24]2)=[O:19])([CH3:16])([CH3:15])[CH3:14]

Participants

3

Reactant 2

HCID 187874442,3-Dihydro-1-benzofuran-4-carboxylic acidHCID 58104588HCID 58104588, compound

Product 1

HCID 66844868HCID 66844868, compound

Procedure

prepared by reaction of 2,3-Dihydro-benzofuran-4-carboxylic acid with (1S,3S,5S)-3-aminomethyl-2-azabicyclo[3.3.0]octane-2-carboxylic acid tert-butyl ester. LC-MS: tR=1.00 min; [M+H]+=387.1.

Sources & evidence

ORD record
ord-0f09110bf1834104bfb6b3ae7f309b67
Source dataset
uspto-grants-2012_10
Patent number
US08288429B2

Reaction notes

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