HCID 87452682, compound → HCID 87371660, compound

Participants

Reaction Steps

Dissolve the compound obtained in Step D (1.47×10−3 mol) in 20 ml of a 4N solution of HCl in 1,4-dioxane and place under stirring. The initially yellowish reaction mixture becomes darker and darker until it is virtually black. After stirring for 18 hours at ambient temperature, the reaction mixture is evaporated to dryness under reduced pressure. The black residue obtained is chromatographed on a silica column using as eluant a 50/50 n-heptane/ethyl acetate mixture.

Provenance & Evidence