4-Aminobenzoic Acid → HCID 20887646, compound

HRID 2064551Notes

Reaction equation

HRID 2064551 reaction equation
[CH3:1][CH:2]1[CH2:7][CH2:6][C:5](=O)[CH:4]([CH2:9][C:10](=O)[CH3:11])[CH2:3]1.[NH2:13][C:14]1[CH:22]=[CH:21][C:17]([C:18]([OH:20])=[O:19])=[CH:16][CH:15]=1>>[CH3:11][C:10]1[N:13]([C:14]2[CH:22]=[CH:21][C:17]([C:18]([OH:20])=[O:19])=[CH:16][CH:15]=2)[C:5]2[CH2:6][CH2:7][CH:2]([CH3:1])[CH2:3][C:4]=2[CH:9]=1

Participants

3

Reactant 2

HCID 9784-Aminobenzoic AcidHCID 24974245HCID 24974245, compound

Product 1

HCID 20887646HCID 20887646, compoundYield 66%

Procedure

Following the general methods as outlined under Intermediate 7, starting from 4-methyl-2-(2-oxopropyl)cyclohexanone and 4-aminobenzoic acid, the title compound was isolated, in 66% yield (98% purity by HPLC). MS(ESI+): 270.5; MS(ESI−): 268.4.

Sources & evidence

ORD record
ord-e0ab5ec8fd5041a58266441bc4b1806b
Source dataset
uspto-grants-2012_10
Patent number
US08288432B2

Reaction notes

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