HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Aminobenzoic Acid → 4-(5-methyl-2-phenyl-4,5,6,7-tetrahydro-1H-indol-1-yl)benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Aminobenzoic Acid | HCID 978 | — |
| Reactant | 4-Methyl-2-(2-oxo-2-phenylethyl)cyclohexanone | HCID 12270340 | — |
| Product | 4-(5-methyl-2-phenyl-4,5,6,7-tetrahydro-1H-indol-1-yl)benzoic acid | HCID 20887555 | 73% |
Reaction Steps
Following the general methods as outlined under Intermediate 13, starting from 4-methyl-2-(2-oxo-2-phenylethyl)cyclohexanone and 4-aminobenzoic acid, the title compound was isolated in 73% yield (95% purity by HPLC). MS(ESI+): 332.5; MS(ESI−): 330.4.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08288432B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-4d4efe233b924749949db68259d6b8aa |
| Source note | uspto-grants-2012_10 |