4-Aminobenzoic Acid → HCID 68595220, compound

HRID 2064553Notes

Reaction equation

HRID 2064553 reaction equation
O=[C:2]([CH3:11])[CH2:3][CH:4]1[CH2:9][CH2:8][CH2:7][CH2:6][C:5]1=O.[NH2:12][C:13]1[CH:21]=[CH:20][C:16]([C:17]([OH:19])=[O:18])=[CH:15][CH:14]=1>>[CH3:11][CH:2]1[CH2:3][CH:4]2[CH:5]([CH2:6][CH2:7][CH2:8][CH2:9]2)[N:12]1[C:13]1[CH:21]=[CH:20][C:16]([C:17]([OH:19])=[O:18])=[CH:15][CH:14]=1

Participants

3

Reactant 2

HCID 9784-Aminobenzoic AcidHCID 5385812-(2-Oxopropyl)cyclohexanone

Product 1

HCID 68595220HCID 68595220, compoundYield 65%

Procedure

Following the general methods as outlined under Intermediate 13, starting from 2-(2-oxopropyl)cyclohexanone and 4-aminobenzoic acid, the title compound was isolated in 65% yield (98% purity by HPLC). MS(ESI+): 256.4; MS(ESI−): 254.4.

Sources & evidence

ORD record
ord-6d69cbd375ce44e0bb1dccc261709852
Source dataset
uspto-grants-2012_10
Patent number
US08288432B2

Reaction notes

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