HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Aminobenzoic Acid → 3-(5-methyl-2-phenyl-4,5,6,7-tetrahydro-1H-indol-1-yl)benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Aminobenzoic Acid | HCID 7419 | — |
| Reactant | 4-Methyl-2-(2-oxo-2-phenylethyl)cyclohexanone | HCID 12270340 | — |
| Product | 3-(5-methyl-2-phenyl-4,5,6,7-tetrahydro-1H-indol-1-yl)benzoic acid | HCID 59214473 | 69% |
Reaction Steps
Following the general methods as outlined under Intermediate 13, starting from 4-methyl-2-(2-oxo-2-phenylethyl)cyclohexanone and 3-aminobenzoic acid, the title compound was isolated in 69% yield (98% purity by HPLC). MS(ESI+): 332.4; MS(ESI−): 330.6.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08288432B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-d080ced523e14ac29a823b3e84e19d52 |
| Source note | uspto-grants-2012_10 |