5,6-Dimethylbenzimidazole → HCID 178477267, compound

HRID 2064591Notes

Reaction equation

HRID 2064591 reaction equation
[CH3:1][C:2]1[C:26]([CH3:27])=[CH:25][C:5]2[N:6](COCC[Si](C)(C)C)[C:7]([C:9]3[CH:13]=[C:12]([S:14][CH2:15][CH3:16])[NH:11][N:10]=3)=[N:8][C:4]=2[CH:3]=1.CC1C(C)=CC2NC=NC=2C=1>>[CH2:15]([S:14][C:12]1[NH:11][N:10]=[C:9]([C:7]2[NH:8][C:4]3[CH:3]=[C:2]([CH3:1])[C:26]([CH3:27])=[CH:25][C:5]=3[N:6]=2)[CH:13]=1)[CH3:16]

Participants

3

Reactant 2

HCID 6755,6-DimethylbenzimidazoleHCID 178477266HCID 178477266, compound

Product 1

HCID 178477267HCID 178477267, compound

Procedure

By proceeding in a similar manner to Example 230(a) above but using 5,6-dimethyl-2-(5-ethylsulfanyl-1H-pyrazol-3-yl)-1-(2-trimethylsilanyl-ethoxymethyl)-1H-benzoimidazole [Reference Example 1(f)] there was prepared 2:5-ethylsulfanyl-1H-pyrazol-3-yl)-5,6-dimethyl-1H-benzoimidazole. LC-MS (METHOD A): RT=2.32 minutes; 273 (M+H)+.

Workup

  1. customwas prepared 2

Sources & evidence

ORD record
ord-97b8275b7db54f278a49af399c39a2a5
Source dataset
uspto-grants-2012_10
Patent number
US08288425B2

Reaction notes

Loading…