HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-6-(trifluoromethyl)aniline → 4-(2-Chloro-6-(trifluoromethyl)phenylamino)-8-(cyclopentyloxy)-7-methoxy-2H-chromen-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-6-(trifluoromethyl)aniline | HCID 2756384 | — |
| Reactant | 4-chloro-8-(cyclopentyloxy)-7-methoxy-2H-chromen-2-one | HCID 77174794 | — |
| Product | 4-(2-Chloro-6-(trifluoromethyl)phenylamino)-8-(cyclopentyloxy)-7-methoxy-2H-chromen-2-one | HCID 24849478 | — |
Reaction Steps
The title compound was prepared from 2-chloro-6-(trifluoromethyl)aniline and 4-chloro-8-(cyclopentyloxy)-7-methoxy-2H-chromen-2-one following the procedure outlined in Example 16. 1H NMR (400 MHz, DMSO-d6): δ 9.34 (s, 1H), 8.05 (d, 1H), 7.93 (d, 1H), 7.91 (d, 1H), 7.71 (t, 1H), 7.18 (d, 1H), 4.82 (m, 1H), 4.29 (s, 1H), 3.90 (s, 3H), 1.90-1.45 (m, 8H); MS (ESI): 453.9.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07745646B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-d86b8f5612824bd7a47af2d076f290a2 |
| Source note | uspto-grants-2010_06 |