3-Furoyl chloride → HCID 178422292, compound

HRID 2064612Notes

Reaction equation

HRID 2064612 reaction equation
O1C=CC(C(Cl)=O)=[CH:2]1.[CH3:9][C:10]1[C:31]([CH3:32])=[CH:30][C:13]2[NH:14][C:15]([C:17]3[C:21]([NH:22][C:23]([C:25]4[CH:29]=[CH:28][O:27][CH:26]=4)=[O:24])=[CH:20][NH:19][N:18]=3)=[N:16][C:12]=2[CH:11]=1>>[CH3:32][C:31]1[C:10]([CH3:9])=[CH:11][C:12]2[N:16]([CH3:2])[C:15]([C:17]3[C:21]([NH:22][C:23]([C:25]4[CH:29]=[CH:28][O:27][CH:26]=4)=[O:24])=[CH:20][NH:19][N:18]=3)=[N:14][C:13]=2[CH:30]=1

Participants

3

Reactant 2

HCID 27761233-Furoyl chlorideHCID 178422293HCID 178422293, compound

Product 1

HCID 178422292HCID 178422292, compound

Procedure

By proceeding in a manner similar to Example 248 (a) above but using 3-furoylchloride there was prepared furan-3-carboxylic acid [3-(5,6-dimethyl-1H-benzoimidazol-2-yl)-1H-pyrazol-4-yl]-amide (80 mg) as a white solid. LC-MS (METHOD L): RT=7.10 minutes, 322.31 (M+H)+.

Sources & evidence

ORD record
ord-144a6adc47174954b9dde59dfb77553c
Source dataset
uspto-grants-2012_10
Patent number
US08288425B2

Reaction notes

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