HCID 178466758, compound → HCID 178466042, compound

HRID 2064617Notes

Reaction equation

HRID 2064617 reaction equation
[NH2:1][C:2]1[CH:7]=[C:6]([O:8][CH2:9][CH3:10])[CH:5]=[CH:4][C:3]=1[NH:11][C:12]([C:14]1[C:18]([N+:19]([O-:21])=[O:20])=[CH:17][NH:16][N:15]=1)=O.[N+](C1C(N2C3C=CC=CC=3N=C2)=NNC=1)([O-])=O>>[CH2:9]([O:8][C:6]1[CH:5]=[CH:4][C:3]2[NH:11][C:12]([C:14]3[C:18]([N+:19]([O-:21])=[O:20])=[CH:17][NH:16][N:15]=3)=[N:1][C:2]=2[CH:7]=1)[CH3:10]

Participants

3

Reactant 2

HCID 178466758HCID 178466758, compoundHCID 178526867HCID 178526867, compound

Product 1

HCID 178466042HCID 178466042, compound

Procedure

By proceeding in a manner similar to Example 252(b) above but using 4-nitro-1H-pyrazole-3-carboxylic acid (2-amino-4-ethoxy-phenyl)-amide [824 mg, Reference Example 36(e)] there was prepared 5-ethoxy-2-(4-nitro-1H-pyrazol-3-yl-1H-benzoimidazole (407 mg) as a light brown powder. LC-MS (Method H): RT=1.82 minutes, 274.26 (M+H)+, 272.30 (M−H)−.

Sources & evidence

ORD record
ord-ec28fc2cb8fc446dac42df82123c0d4c
Source dataset
uspto-grants-2012_10
Patent number
US08288425B2

Reaction notes

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