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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2064712Generated: November 2, 2026

Thioacetamide → 5-(3-Fluoro-4-methyl-phenyl)-2-methyl-thiazole-4-carboxylic Acid Methyl Ester

https://huagongshe.com/reaction/2064712

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThioacetamideHCID 2723949—
Reactant3-Chloro-3-(3-fluoro-4-methyl-phenyl)-2-oxo-propionic acid methyl esterHCID 64898287—
Product5-(3-Fluoro-4-methyl-phenyl)-2-methyl-thiazole-4-carboxylic Acid Methyl EsterHCID 66865670—

Reaction Steps

prepared by reaction of 3-chloro-3-(3-fluoro-4-methyl-phenyl)-2-oxo-propionic acid methyl ester with thioacetamide. LC-MS: tR=1.00 min; [M+H]+=266.0.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08288435B2
Source datasetuspto-grants-2012_10
ORD IDord-73b6d7a64f0f434b96a5f22eb597c802
Source noteuspto-grants-2012_10