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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2064717Generated: November 2, 2026

Thioacetamide → 2-Methyl-5-(3-nitrophenyl)thiazole-4-carboxylic acid methyl ester

https://huagongshe.com/reaction/2064717

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThioacetamideHCID 2723949—
ReactantMethyl 3-(3-nitrophenyl)-3-chloro-2-oxopropionateHCID 12193327—
Product2-Methyl-5-(3-nitrophenyl)thiazole-4-carboxylic acid methyl esterHCID 66844630—

Reaction Steps

prepared by reaction of 3-chloro-3-(3-nitro-phenyl)-2-oxo-propionic acid methyl ester with thioacetamide. LC-MS: tR=0.94 min; [M+H]+=279.3.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08288435B2
Source datasetuspto-grants-2012_10
ORD IDord-3fbce9473e454f5d801d2c5d21b2797f
Source noteuspto-grants-2012_10