HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopropanecarbothioamide → 2-Cyclopropyl-5-(3-fluoro-phenyl)-thiazole-4-carboxylic Acid Methyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopropanecarbothioamide | HCID 22140884 | — |
| Reactant | Methyl 3-chloro-3-(3-fluorophenyl)-2-oxopropanoate | HCID 57437155 | — |
| Product | 2-Cyclopropyl-5-(3-fluoro-phenyl)-thiazole-4-carboxylic Acid Methyl Ester | HCID 66866670 | — |
Reaction Steps
prepared by reaction of 3-chloro-3-(3-fluoro-phenyl)-2-oxo-propionic acid methyl ester with cyclopropanecarbothioic acid amide. LC-MS: tR=1.02 min; [M+H]+=278.0.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08288435B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-a639260e5ec446c0b8bf9f23dc275a7e |
| Source note | uspto-grants-2012_10 |