Cyclopropanecarbothioamide → HCID 66844913, compound

HRID 2064721Notes

Reaction equation

HRID 2064721 reaction equation
[CH3:1][O:2][C:3](=[O:15])[C:4](=O)[CH:5](Cl)[C:6]1[CH:11]=[CH:10][C:9]([F:12])=[CH:8][CH:7]=1.[CH:16]1([C:19](=[S:21])[NH2:20])[CH2:18][CH2:17]1>>[CH3:1][O:2][C:3]([C:4]1[N:20]=[C:19]([CH:16]2[CH2:18][CH2:17]2)[S:21][C:5]=1[C:6]1[CH:11]=[CH:10][C:9]([F:12])=[CH:8][CH:7]=1)=[O:15]

Participants

3

Reactant 2

HCID 22140884CyclopropanecarbothioamideHCID 57437156Methyl 3-chloro-3-(4-fluorophenyl)-2-oxopropanoate

Product 1

HCID 66844913HCID 66844913, compound

Procedure

prepared by reaction of 3-chloro-3-(4-fluoro-phenyl)-2-oxo-propionic acid methyl ester with cyclopropanecarbothioic acid amide. LC-MS: tR=1.01 min; [M+H]+=278.3.

Sources & evidence

ORD record
ord-24d925980f3a419da395ad68e2bff717
Source dataset
uspto-grants-2012_10
Patent number
US08288435B2

Reaction notes

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