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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2064723Generated: November 2, 2026

Cyclopropanecarbothioamide → 2-Cyclopropyl-5-p-tolyl-thiazole-4-carboxylic acid methyl ester

https://huagongshe.com/reaction/2064723

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopropanecarbothioamideHCID 22140884—
ReactantMethyl 3-chloro-2-oxo-3-(p-tolyl)propanoateHCID 57437153—
Product2-Cyclopropyl-5-p-tolyl-thiazole-4-carboxylic acid methyl esterHCID 66866714—

Reaction Steps

prepared by reaction of 3-chloro-2-oxo-3-p-tolyl-propionic acid methyl ester with cyclopropanecarbothioic acid amide. LC-MS: tR=1.04 min; [M+H]+=274.4.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08288435B2
Source datasetuspto-grants-2012_10
ORD IDord-bf4abdc7c0204170967d2730592ea9f4
Source noteuspto-grants-2012_10