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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2064728Generated: November 1, 2026

Thiourea → Methyl 2-amino-5-(4-fluorophenyl)-1,3-thiazole-4-carboxylate

https://huagongshe.com/reaction/2064728

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThioureaHCID 2723790—
ReactantMethyl 3-chloro-3-(4-fluorophenyl)-2-oxopropanoateHCID 57437156—
ProductMethyl 2-amino-5-(4-fluorophenyl)-1,3-thiazole-4-carboxylateHCID 2782963—

Reaction Steps

prepared by reaction of 3-chloro-3-(4-fluoro-phenyl)-2-oxo-propionic acid methyl ester with thiourea. LC-MS: tR=0.75 min; [M+H]+=253.2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08288435B2
Source datasetuspto-grants-2012_10
ORD IDord-5281b945e612458eb20bb49652d8d2b2
Source noteuspto-grants-2012_10