3-Bromobenzoic acid → HCID 67081290, compound

HRID 2064800Notes

Reaction equation

HRID 2064800 reaction equation
[C:1]([O:5][C:6]([N:8]1[C@H:13]([CH2:14][NH2:15])[CH2:12][C@H:11]2[C@@H:9]1[CH2:10]2)=[O:7])([CH3:4])([CH3:3])[CH3:2].[Br:16][C:17]1[CH:18]=[C:19]([CH:23]=[CH:24][CH:25]=1)[C:20](O)=[O:21]>>[C:1]([O:5][C:6]([N:8]1[C@H:13]([CH2:14][NH:15][C:20](=[O:21])[C:19]2[CH:23]=[CH:24][CH:25]=[C:17]([Br:16])[CH:18]=2)[CH2:12][C@H:11]2[C@@H:9]1[CH2:10]2)=[O:7])([CH3:4])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 114563-Bromobenzoic acidHCID 58278675(1S,3S,5S)-tert-Butyl 3-(aminomethyl)-2-azabicyclo[3.1.0]hexane-2-carboxylate

Product 1

HCID 67081290HCID 67081290, compound

Procedure

prepared by reaction of (1S,3S,5S)-3-aminomethyl-2-aza-bicyclo[3.1.0]hexane-2-carboxylic acid tert-butyl ester with 3-bromo-benzoic acid. LC-MS (acidic): tR=1.08 min; [M+H]+=394.9.

Sources & evidence

ORD record
ord-2b4f5dbad99b44f5b3f88161c84e1110
Source dataset
uspto-grants-2012_10
Patent number
US08288435B2

Reaction notes

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