8-Quinolinecarboxylic acid → HCID 67081206, compound

HRID 2064801Notes

Reaction equation

HRID 2064801 reaction equation
[C:1]([O:5][C:6]([N:8]1[C@H:13]([CH2:14][NH2:15])[CH2:12][C@H:11]2[C@@H:9]1[CH2:10]2)=[O:7])([CH3:4])([CH3:3])[CH3:2].[N:16]1[C:25]2[C:20](=[CH:21][CH:22]=[CH:23][C:24]=2[C:26](O)=[O:27])[CH:19]=[CH:18][CH:17]=1>>[C:1]([O:5][C:6]([N:8]1[C@H:13]([CH2:14][NH:15][C:26]([C:24]2[CH:23]=[CH:22][CH:21]=[C:20]3[C:25]=2[N:16]=[CH:17][CH:18]=[CH:19]3)=[O:27])[CH2:12][C@H:11]2[C@@H:9]1[CH2:10]2)=[O:7])([CH3:4])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 665828-Quinolinecarboxylic acidHCID 58278675(1S,3S,5S)-tert-Butyl 3-(aminomethyl)-2-azabicyclo[3.1.0]hexane-2-carboxylate

Product 1

HCID 67081206HCID 67081206, compound

Procedure

prepared by reaction of (1S,3S,5S)-3-aminomethyl-2-aza-bicyclo[3.1.0]hexane-2-carboxylic acid tert-butyl ester with quinoline-8-carboxylic acid. LC-MS (acidic): tR=0.95 min; [M+H]+=368.1.

Sources & evidence

ORD record
ord-f0bc4ba453a9478fb0eeb6e8ace1f255
Source dataset
uspto-grants-2012_10
Patent number
US08288435B2

Reaction notes

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