HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methyl-5-(2-trifluoromethyl-phenyl)-thiazole-4-carboxylic acid → benzofuran-4-carboxylic acid {(1S,3S,5S)-2-[2-methyl-5-(2-trifluoromethyl-phenyl)-thiazole-4-carbonyl]-2-aza-bicyclo[3.1.0]hex-3-ylmethyl}-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methyl-5-(2-trifluoromethyl-phenyl)-thiazole-4-carboxylic acid | HCID 57437176 | — |
| Reactant | benzofuran-4-carboxylic acid [(1S,3S,5S)-2-aza-bicyclo[3.1.0]hex-3-ylmethyl]-amide | HCID 67081492 | — |
| Product | benzofuran-4-carboxylic acid {(1S,3S,5S)-2-[2-methyl-5-(2-trifluoromethyl-phenyl)-thiazole-4-carbonyl]-2-aza-bicyclo[3.1.0]hex-3-ylmethyl}-amide | HCID 67081237 | — |
Reaction Steps
prepared by reaction of benzofuran-4-carboxylic acid [(1S,3S,5S)-2-aza-bicyclo[3.1.0]hex-3-ylmethyl]-amide with 2-methyl-5-(2-trifluoromethyl-phenyl)-thiazole-4-carboxylic acid. LC-MS (basic): tR=1.43 min; [M+H]+=526.1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08288435B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-9abcf45268c74c1aa406ff3602d1b02f |
| Source note | uspto-grants-2012_10 |