HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-5-m-tolyl-thiazole-4-carboxylic acid → benzofuran-4-carboxylic acid [(1S,3S,5S)-2-(2-amino-5-m-tolyl-thiazole-4-carbonyl)-2-aza-bicyclo[3.1.0]hex-3-ylmethyl]-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-5-m-tolyl-thiazole-4-carboxylic acid | HCID 53271742 | — |
| Reactant | benzofuran-4-carboxylic acid [(1S,3S,5S)-2-aza-bicyclo[3.1.0]hex-3-ylmethyl]-amide | HCID 67081492 | — |
| Product | benzofuran-4-carboxylic acid [(1S,3S,5S)-2-(2-amino-5-m-tolyl-thiazole-4-carbonyl)-2-aza-bicyclo[3.1.0]hex-3-ylmethyl]-amide | HCID 86653646 | — |
Reaction Steps
prepared by reaction of benzofuran-4-carboxylic acid [(1S,3S,5S)-2-aza-bicyclo[3.1.0]hex-3-ylmethyl]-amide with 2-amino-5-m-tolyl-thiazole-4-carboxylic acid. LC-MS (basic): tR=1.33 min; [M+H]+=473.1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08288435B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-5bb64af0c44b43a398fa5b2531e51b8e |
| Source note | uspto-grants-2012_10 |